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Visit the Princess Bar in Lowtown. Ask for "Patch".
Defeat 100 supervillains in Midtown Manhattan.
Create any runeword on an Uru-Forged item.
Apply a Costume Core to any costume.
Level any Vendor to level 20.
Defeat Madame Hydra in the Holo-Sim and collect the chest reward from the VIP wave.
Complete Wave 10 in the S.H.I.E.L.D. Holo-Sim.
Collect the "special" items.
Defeat every supervillain who appears in the Industry City patrol zone.
As Iron Man, reach level 60.
Go get to level 60 as me, Deadpool. It's not that hard!
As Scarlet Witch, reach level 60.
Defeat 1,000 Red Hydra members in the March to Axis One-Shot.
Complete Wave 10 in X-Defense.
As Storm, reach level 60.
Loot 2,002 Eternity Splinters.
As Cyclops, reach level 60.
Complete each Legendary Quest in Midtown Manhattan.
As Captain America, reach level 60.
As Wolverine, reach level 60.
As Hulk, reach level 60.
As Spider-Man, reach level 60.
As Jean Grey, reach level 60.
As Thor, reach level 60.
As Gambit, reach level 60.
As Doctor Doom, reach level 60.
As Rocket Raccoon, reach level 60.
As Hawkeye, reach level 60.
As Daredevil, reach level 60.
As Rogue, reach level 60.
As Nightcrawler, reach level 60.
As Doctor Strange, reach level 60.
As Venom, reach level 60.
As Ghost Rider, reach level 60.
As Loki, reach level 60.
Stop the nefarious No-Good Alex Williams in his campaign to deface the panoramic views of Midtown Manhattan with graffiti.
As Black Widow, reach level 60.
As Captain Marvel, reach level 60.
As Cable, reach level 60. See you around.
As War Machine, reach level 60.
As Magik, reach level 60.
As Iceman, reach level 60.
As Emma Frost, reach level 60.
As Colossus, reach level 60.
As X-23, reach level 60.
As Black Panther, reach level 60.
As Juggernaut, reach level 60.
As Psylocke, reach level 60.
As Human Torch, reach level 60.
As Silver Surfer, reach level 60.
As Magneto, reach level 60.
As Star-Lord, reach level 60.
As Thing, reach level 60.
As Squirrel Girl, reach level 60.
As Punisher, reach level 60.
As Luke Cage, reach level 60.
As Taskmaster, reach level 60.
As Ant-Man, reach level 60.
As Vision, reach level 60.
As Moon Knight, reach level 60.
Fully unlock 50 heroes.
As Winter Soldier, reach level 60.
As Invisible Woman, reach level 60.
As Nova, reach level 60.
As Blade, reach level 60.
As Iron Fist, reach level 60.
As Black Cat, reach level 60.
As She-Hulk, reach level 60.
Defeat 100 supervillains in X-Defense.
Defeat 100 holographic supervillains in the S.H.I.E.L.D. Holo-Sim.
As Kitty Pryde, reach level 60.
As Green Goblin, reach level 60.
As Elektra, reach level 60.
As Ultron, reach level 60.
As Angela, reach level 60.
Complete a solo run of the March to Axis One-Shot with Captain America.
As Mr. Fantastic, reach level 60.
Have 1 hero at level 60 Cosmic Prestige.
Complete a solo run of the Bronx Zoo One-Shot with Spider-Man.
In a solo Cosmic Terminal run, defeat Doctor Doom in under 60 seconds upon entering his throne room. You must be present for the entire fight.
Explore all of the Treasure Rooms in each chapter of Story Mode.
Complete a solo run of the Vibranium Mines One-Shot with Black Panther.
Defeat Ultron within 8 minutes of initially entering the Game Mode.
Earn over 9,000 Achievement Points.
Defeat 17 different mutant heroes in PvP.
Craft a Portal to the Confidential Bovine Sector.
Defeat any 10 opponents in PvP using 50 different heroes.
Unlock 10 titles.
Defeat Surtur 50 times in the Muspelheim Raid.
Defeat 50 different heroes in PvP.
Defeat Mister Sinister's cloned X-Men 100 times.